On disabling the On-Access Scan, Trellix remains registered as your active antivirus in Windows Security Center.
Select Menu → Policy → Policy Catalog, then select Endpoint Security Threat Prevention from the Products list in the left pane.
From the Category list in the right pane, select On-Access Scan.
Click the Edit link for an editable policy.
Click Show Advanced.
Under On-Access Scan, select Disable.
Click Save.