Use a client task to run a predefined Full Scan or Quick Scan on computers in the System Tree.
Configure the behavior of quick and full scans in the On-Demand Scan policy settings.
Task
(Optional) Configure the behavior for the scan in the On-Demand Scan policy settings.
Select Menu → Client Tasks → Client Task Catalog.
From Client Task Types, select Endpoint Security Threat Prevention → Policy Based On-Demand Scan.
Under Actions for the scan type, click the Assign link, specify the computers to assign the task to, then click OK.
Click 2 Schedule to schedule the task, then click Save.
See ePO - On-prem Help for schedule information and the Client Task Assignment Builder.